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Ganglionic and adrenergic blocking drugs should only be combined with ramipril under careful supervision.	Bar graphs show effect on urine volume (uv) induced by ramipril (2.	High risk individuals unable to take ramipril because of side effects are directed to the parallel study, transcend, which uses an identical treatment protocol and outcome measures as ontarget, but in which randomization is to telmistran or placebo.

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